BSU scientist researches Streptococcus mutans after exposure to sucrose and starch

10/01/2023

A scientific paper entitled “Comparing proteome changes involved in biofilm formation by Streptococcus mutans after exposure to sucrose and starch” by Professor Khudaverdi Ganbarov, Head of The Research Laboratory of Microbiology and Virology of the Center of Excellence for Research, Development and Innovation of Baku State University (BSU) was published by “Biotechnology and Applied Biochemistry”.

Streptococcus mutans is a main organism of tooth infections including tooth decay and periodontitis. The aim of this study was to assess the influence of sucrose and starch on biofilm formation and proteome profile of S. mutans ATCC 35668 strain. The biofilm formation was assessed by microtiter plating method. Changes in bacterial proteins after exposure to sucrose and starch carbohydrates were analyzed using matrix-assisted laser desorption/ionization mass spectrometry. The biofilm formation of S. mutans was increased to 391.76% in 1% sucrose concentration, 165.76% in 1% starch, and 264.27% in the 0.5% sucrose plus 0.5% starch in comparison to biofilm formation in the media without sugars.

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